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Pharmacology

The study of Pharmacology enables us to examine the effect of drugs on various human systems and the various ways the body deals with the drugs. It includes general pharmacology, systemic pharmacology and chemotherapy which is the study of the action of drugs on microorganisms, parasites or cancer cells that grow and multiply in the human body.
Pharmacology is an important basic medical science that is essential for the basic doctor to prescribe rationally and optimally for the patient he/she is treating. It is essential therefore to equip our medical students with a sound base in pharmacology so that he/she comprehends how drugs are absorbed, distributed, bound to receptors, initiate complex responses and then get bio-transformed and eliminated.
Developing a sound framework of the concepts and principles of drug action will stand the student in good stead as he moves into internship and starts prescribing for the patient. This is what the World Health Organisation states will enable physicians to prescribe rationally. In the “Guide to Good Prescribing,” brought out by the WHO, medical students are taught the six steps of how to prescribe rationally and optimise drugs for the patient by applying the criteria  –  efficacy, safety, suitability and cost.
A clinician well-grounded in the concepts of the basic sciences is the one who will be able to apply his knowledge to provide rational therapy for his/her patient. It is no secret that a large majority of Nobel prize winners were pharmacologists or had a strong base in pharmacology.


HISTORY
The Pharmacology department was founded in 2002 when the Malankara Orthodox Medical Mission Hospital was upgraded to become a Medical College. The department of Pharmacology was established under the leadership of Dr Lillykutty L.
Professor Dr. Hariharan TS joined the department in March 2003 and has rendered yeoman service to the department by establishing good systems, teaching modules and innovative practical exercises in the department. His presence in the department for the last14 years have brought stability and academic quality to the department.
This year we will be sending up the fourteenth batch of students for the pharmacology examinations. The pharmacology course has an innovative combination of didactic lectures and small group teaching with necessary media and teaching aids such as algorithms, charts, graphs, sample medications and demonstrations. With the removal of animal experimentation from the course curriculum we hope to introduce more computer assisted learning in our teaching of pharmacology.
We would like medical students to learn the principles of research methodology and develop a spirit of enquiry and lateral thinking and therefore since 2014 we have been encouraging medical students to submit research projects for the short term studentship (STS) programme of the Indian Medical Council of Research.
Since 2015 we have an ongoing Pharmacovigilance programme and with the help of the ward sisters we are able to monitor adverse drug reactions that are reported in the hospital.


ACADEMICS
The Learning Objectives Of The Pharmacology MBBS Course
At the end of the course the student should be able to

  • Elucidate the basic pharmacology, pharmacodynamics, pharmacokinetics, indications and adverse drug effects of the essential and commonly used drugs.
  • Apply the basic principles of Pharmacology and Therapeutics while describing these drugs.
  • Select and prescribe drugs rationally for common conditions and communicable diseases and be aware of the drug therapies under the National Health Programmes.
  • Write rational prescriptions using the principles outlined in the WHO module “Guide to Good Prescribing”
  • Elaborate the principles of management of poisoning and indications of specific antidotes for drug toxicity.
  • Outline the principles of pharmacovigilance and reporting of adverse drug reactions
  • Enumerate the basic principles of pharmacoeconomics, pharmacogenetics, pharmacogenomics. and evidenced based medicine.
  • Inculcate a spirit of enquiry, critical thinking and good practices in research by encouraging students to undertake research projects.

Teaching-Learning Activities of the Pharmacology Department

  • Theory classes in pharmacology. Classes are held for MBBS students, nursing students and various courses for technicians.
  • Practical classes in Pharmacology. Practicals are conducted in groups and use several teaching learning methods such as demonstrations, seminars, group discussions, tutorials etc. Videos
  • Prescription writing sessions. Students prepare prescriptions and learn how to critically reason out optimal drugs for the patient. They are held in seminar format towards the end of the MBBS course using the six – step process initiated by the WHO. Students are encouraged to make their own  p-drugs and p-formulary.
  • Assessments. Three sessional examinations and periodic class tests and quizzes are conducted besides remedial measures and mentoring for students with poor attendance and marks.

Departmental Activities

  • Academic meetings. Academic meetings are held every Thursday to keep abreast of current issues in pharmacology and to update our knowledge about new medical knowledge.
  • Pharmacovigilance Cell. The adverse drug reactions reported from various wards and out-patient services of the institution are collated and maintained.
  • Institutional Research Board. A member of the faculty co-ordinates the research activities in the institution and takes part in the scientific review of the research projects undertaken by students and faculty.
  • Institutional Ethics Committee. A member of the faculty participates in the ethics committee as the Basic Science member.
  • Regional National Tuberculosis Control Programme (RNTCP) Core Committee. The Head of the Department is a member of the Core Committee and participates in the deliberations of this committee.

Research Activities of the Department

 

Current areas of research work

Faculty involved

i.

Antibiotic audit in the affiliated hospital

Susan Mani, Nisha M

ii

Prevalence of Potentially Inappropriate medications (PIMs) prescribed for the elderly and factors predisposing to it in a tertiary care centre.

Arun Bhatt, Anna Mathew

iii.

Adverse Drug reactions occurring in a tertiary care centre

Jolly Varghese, Anna Mathew

iv.

Polypharmacy And Drug Interactions In Elderly Patients

Lily Magna (2012), Jolly Varghese, Anna Mathew

v.

Perceptions on pre-school education, supplementary nutrition and immunisation of children in the community

Vishnupriya V (2011), Nisha M, Anna Mathew

vi.

The profile of infants born to mothers with subclinical hypothyroidism in a tertiary care centre

Hareesh MV (2011), Asha Biju, Anna Mathew

vii.

Antibiotic Susceptibility Pattern of Klebsiella pneumonia isolated from cases of Urinary tract Infection in a Tertiary Care Centre

Anila Varghese (2011), Shareen George, Anna Mathew

viii.

Comparison of Breast feeding and 25% Oral Dextrose for Pain Relief during Immunization of Infants - A Randomised Controlled Trial

Nivedita Mohan (2011), Abraham Paulose, Anna Mathew

ix.

A Study of the Effects of the Radiofrequency Waves of Cell Phones on the Thyroid Function of Mobile Phone Users: A Cross sectional Study

Nikita Mary Baby (2011) George Koshy, Anna Mathew

x.

The Incidence of Thrombophlebitis following the use of Peripheral Intravenous Cannulae in Post-operative Patients

Jisal Saji (2011), Sara Vergis, Anna Mathew.

xi.

Sleep Behaviour and Academic Grade of Early Adolescent School going Children in a Rural Area

Thomas Jeo Joseph (2011), M C Mathew, Anna Mathew

xii.

A Study to Validate blood pressure measurements by lay volunteers for community blood pressure measurements.

Thomas Jeo Joseph (2011), M C Mathew, Anna Mathew

xiii.

The Role of structured education in Improving Medication Adherance in Type-2 Diabetic patients in a rural tertiary care centre. A Randomised Control Trial

Kiron Jacob Joncy (2012) Anna Mathew

xiv.

The role of structured education in improving awareness and acceptance of labour analgesia among parturient mothers

Ambili Anu Isaac (2012), Sara vergis, Anna Mathew

xv.

Medical students perception of undergraduate educational environment during first clinical year and final year of study in a rural medical college

Deepsha James (2012), Susan Mani, Anna Mathew

 

xvi.

A Crosssectional study on Sleep Behaviour , Body mass Index and Waist-hip ratio in adolescent children studying in a rural area

Lenny S Mathew (2012), M C Mathew, Anna Mathew

xvii.

The Pattern of bacterial Pathogens and their antibiotic Susceptibility Profile From Lower Respiratory Tract Isolates.

Asha M Thomas (2012) Chithra Jayaprakash, Anna Mathew

xviii.

Self-medication practices of medical students studying in a rural medical college before and after learning pharmacology.

Caroline Francis (2013), Serah Johnny, Anna Mathew

xix.

The Role of a Structured Educational Module in Improving Compliance to Anti-hypertensive therapy:A Randomized Controlled Trial

Sachin Daniel (2013), Anna Mathew

xx.

The Role of an educational package in Improving Medication Adherence in Elderly veterans attending an Ex-servicemen’s Clinic: A Randomised Controlled Trial.

Deepa Thomas (2013), Asha Biju, Anna Mathew


 NEWS AND EVENTS

Academic Meetings are held every Thursday at 11 a m where all faculty of MOSC especially those belonging to the pre and para-clinical departments are welcome.

 

Academic Meetings June- August 2016

 

 

 

31.05.2016

 

Dr Serah Johnny

 

Newer methods for post-operative pain relief

 

 

07.06.2016

 

Kiren Jacob Joncy

Asha Mary Thomas

 

 

Drug Adherence in Diabetic patients

Antibiotic susceptibility of LRT pathogens

 

 

14.06.2016

 

 

Dr Jeeji Palocaran

 

Biochemistry of Hyperlipidemia

 

21.06.2016

 

 

Dr Sara Vergis

 

Use of Imidazolines in Anaesthesia

 

28.06.2016

 

 

Dr T S Hariharan

 

Fixed Drug Combinations – Use and Misuse

 

05.07.2016

 

 

Dr Shareen George

 

Rotavirus

 

21.07.2016

 

 

Dr Usha Poothiode

 

Metabolic Syndrome and Cancer

 

28.07.2016

 

 

Dr Susan Mani

 

Warfarin

 

04.08.2016

 

Dr Swapna

 

Methicillin Resistant Staph Aureus (MRSA)

 

18.08.2016

 

Dr Chithra

 

Antibiotic Resistance

 

25.08.2016

 

Dr Minu Liz Abraham

 

Regulation of Blood Sugar


VISION AND MISSION

Vision
The vision of the Department of Pharmacology is
to communicate the concepts of pharmacology to various groups of students in creative and meaningful ways that will inspire students to use drugs effectively and rationally.
to encourage professional development of all faculty members and to enhance professional satisfaction and well-being of each member of the team.

Mission
The mission of the Department of Pharmacology is to enhance learning and education in pharmacology and to integrate the learning of basic medical sciences with clinical skills in the medical school.
Students will develop a spirit of enquiry if they are initiated into the good practices of research methodology early in their medical career and they are encouraged to apply their knowledge and execute good research desiogn in innovative projects.
In this age of evidence based medicine the department of pharmacology encourages research activities and academic development of each of the staff members in the department and encourages continuing professional education and development of new skills. 

Facilities

  • Experimental pharmacology laboratory equipped with all the essential instruments and equipment for demonstration and practice of pharmacy exercises seating 60 students.
  • Clinical pharmacology and pharmacy Laboratory equipped with all the essential instruments and equipment for tissue experiments and demonstration of charts, models and graphs seating 60 students.
  • Demonstration room seating 60 students with mounted LCD projector, overhead projector and computer and accessories.
  • Library. The department has a library with over 100 books
  • Museum. Several charts, diagrams and photographs are displayed  to enable students to learn about actions of drugs. There are also nearly 300 drug samples in a system -wise display. Drug specimens of modern medicine are displayed which enable the undergraduate to gather information regarding sources of drugs, dosage forms, routes of drug administration.

Faculty